{"id":860187,"date":"2022-07-08T10:54:28","date_gmt":"2022-07-08T17:54:28","guid":{"rendered":"https:\/\/new-cm-edgedigital.pages.dev\/en-us\/research\/"},"modified":"2022-07-08T10:54:28","modified_gmt":"2022-07-08T17:54:28","slug":"is-there-a-difference-between-li-rads-3-to-li-rads-5-progression-assessment-using-ct-versus-mr-a-retrospective-single-center-longitudinal-study-of-patients-who-underwent-5082-radiologic-examination","status":"publish","type":"msr-research-item","link":"https:\/\/new-cm-edgedigital.pages.dev\/en-us\/research\/publication\/is-there-a-difference-between-li-rads-3-to-li-rads-5-progression-assessment-using-ct-versus-mr-a-retrospective-single-center-longitudinal-study-of-patients-who-underwent-5082-radiologic-examination\/","title":{"rendered":"Is There a Difference Between LI-RADS 3 to LI-RADS 5 Progression Assessment Using CT Versus MR? A Retrospective, Single-Center, Longitudinal Study of Patients Who Underwent 5082 Radiologic Examinations for Surveillance of Hepatocellular Carcinoma Over a 43-Month Period"},"content":{"rendered":"
\n

Objective<\/h3>\n

The Liver Imaging Reporting and Data System (LI-RADS) has been widely applied to\u00a0CT<\/a>\u00a0and MR liver observations in patients at high-risk for hepatocellular carcinoma (HCC). We investigated the impact of CT vs MR in upgrading LI-RADS 3 to LI-RADS 5 observations using a large cohort of high-risk patients.<\/p>\n<\/div>\n

\n

Methods<\/h3>\n

We performed a retrospective, longitudinal study of CT and MR radiographic reports (June 2013 – February 2017) with an assigned LI-RADS category. A final population of 757 individual scans and 212 high-risk patients had at least one LI-RADS 3 observation. Differences in observation time to progression between modalities were determined using uni- and multivariable analysis.<\/p>\n<\/div>\n

\n

Results<\/h3>\n

Of the 212 patients with a LI-RADS 3 observation, 52 (25%) had progression to LI-RADS 5. Tp ranged from 64 – 818 days (median: 196 days). One hundred and three patients (49%) had MR and 109 patients (51%) had CT as their index study. Twenty-four patients with an MR index exam progressed to LI-RADS 5 during the follow-up interval, with progression rates of 22% (CI:13%-30%) at 1 year and 29% (CI:17%-40%) at 2 years. Twenty-eight patients with a CT index exam progressed to LI-RADS 5 during follow-up, with progression rates of 26% (CI:16%-35%) at 1 year and 31% (CI:19%-41%) at 2 years. Progression rates were not significantly different between patients whose LI-RADS 3 observation was initially diagnosed on MR vs CT (HR: 0.81,\u00a0P<\/em>\u202f=\u202f0.44).<\/p>\n<\/div>\n

\n

Discussion<\/h3>\n

MR and CT modalities are comparable for demonstrating progression from LI-RADS 3 to 5 for high risk patients.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Objective The Liver Imaging Reporting and Data System (LI-RADS) has been widely applied to\u00a0CT\u00a0and MR liver observations in patients at high-risk for hepatocellular carcinoma (HCC). We investigated the impact of CT vs MR in upgrading LI-RADS 3 to LI-RADS 5 observations using a large cohort of high-risk patients. Methods We performed a retrospective, longitudinal study […]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":false,"_classifai_error":"","msr-author-ordering":null,"msr_publishername":"","msr_publisher_other":"","msr_booktitle":"","msr_chapter":"","msr_edition":"","msr_editors":"","msr_how_published":"","msr_isbn":"","msr_issue":"2","msr_journal":"Current Problems in Diagnostic Radiology","msr_number":"","msr_organization":"","msr_pages_string":"","msr_page_range_start":"176","msr_page_range_end":"180","msr_series":"","msr_volume":"51","msr_copyright":"","msr_conference_name":"","msr_doi":"","msr_arxiv_id":"","msr_s2_paper_id":"","msr_mag_id":"","msr_pubmed_id":"","msr_other_authors":"","msr_other_contributors":"","msr_speaker":"","msr_award":"","msr_affiliation":"","msr_institution":"","msr_host":"","msr_version":"","msr_duration":"","msr_original_fields_of_study":"","msr_release_tracker_id":"","msr_s2_match_type":"","msr_citation_count_updated":"","msr_published_date":"2022-3","msr_highlight_text":"","msr_notes":"","msr_longbiography":"","msr_publicationurl":"","msr_external_url":"","msr_secondary_video_url":"","msr_conference_url":"","msr_journal_url":"","msr_s2_pdf_url":"","msr_year":0,"msr_citation_count":0,"msr_influential_citations":0,"msr_reference_count":0,"msr_s2_match_confidence":0,"msr_microsoftintellectualproperty":false,"msr_s2_open_access":false,"msr_s2_author_ids":[],"msr_pub_ids":[],"msr_hide_image_in_river":0,"footnotes":""},"msr-research-highlight":[],"research-area":[13553],"msr-publication-type":[193715],"msr-publisher":[],"msr-focus-area":[],"msr-locale":[268875],"msr-post-option":[],"msr-field-of-study":[],"msr-conference":[],"msr-journal":[],"msr-impact-theme":[],"msr-pillar":[],"class_list":["post-860187","msr-research-item","type-msr-research-item","status-publish","hentry","msr-research-area-medical-health-genomics","msr-locale-en_us"],"msr_publishername":"","msr_edition":"","msr_affiliation":"","msr_published_date":"2022-3","msr_host":"","msr_duration":"","msr_version":"","msr_speaker":"","msr_other_contributors":"","msr_booktitle":"","msr_pages_string":"","msr_chapter":"","msr_isbn":"","msr_journal":"Current Problems in Diagnostic Radiology","msr_volume":"51","msr_number":"","msr_editors":"","msr_series":"","msr_issue":"2","msr_organization":"","msr_how_published":"","msr_notes":"","msr_highlight_text":"","msr_release_tracker_id":"","msr_original_fields_of_study":"","msr_download_urls":"","msr_external_url":"","msr_secondary_video_url":"","msr_longbiography":"","msr_microsoftintellectualproperty":0,"msr_main_download":"","msr_publicationurl":"","msr_doi":"","msr_publication_uploader":[{"type":"url","viewUrl":"false","id":"false","title":"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0363018821000682","label_id":"243109","label":0}],"msr_related_uploader":"","msr_citation_count":0,"msr_citation_count_updated":"","msr_s2_paper_id":"","msr_influential_citations":0,"msr_reference_count":0,"msr_arxiv_id":"","msr_s2_author_ids":[],"msr_s2_open_access":false,"msr_s2_pdf_url":null,"msr_attachments":[],"msr-author-ordering":[{"type":"text","value":"Patricia I. 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