{"id":371189,"date":"2017-03-15T17:22:09","date_gmt":"2017-03-16T00:22:09","guid":{"rendered":"https:\/\/new-cm-edgedigital.pages.dev\/en-us\/research\/?post_type=msr-research-item&#038;p=371189"},"modified":"2018-10-16T20:09:02","modified_gmt":"2018-10-17T03:09:02","slug":"comparison-application-low-concentration-80-phenol-solution-pilonidal-sinus-disease","status":"publish","type":"msr-research-item","link":"https:\/\/new-cm-edgedigital.pages.dev\/en-us\/research\/publication\/comparison-application-low-concentration-80-phenol-solution-pilonidal-sinus-disease\/","title":{"rendered":"Comparison of the application of low concentration and 80% phenol solution in pilonidal sinus disease"},"content":{"rendered":"<h4>OBJECTIVES:<\/h4>\n<p>Many conservative methods have been applied in the treatment of pilonidal sinus disease (PSD). The most commonly used conservative treatment is 80% phenol solution. Our observations demonstrated that 80% phenol solution caused much destruction in the sacrococcygeal region.<\/p>\n<h4>DESIGN:<\/h4>\n<p>In this study low concentrations of phenol were used with the aim of reducing the unwanted side-effects of high-concentration phenol without reducing the therapeutic effects.<\/p>\n<h4>PARTICIPANTS:<\/h4>\n<p>We treated 112 patients (18 women, 94 men) with PSD using phenol solution. Patients were divided into two groups: Group A was treated with a 40% solution of phenol solution, and Group B was treated with an 80% solution of phenol solution.<\/p>\n<h4>SETTING:<\/h4>\n<p>All patients were treated on an outpatient basis. One mL of low (40%) or high (80%) concentration phenol solution was injected into the main sinus orifice. During the check it was observed and noted whether there was skin necrosis, fatty tissue necrosis or abscesses.<\/p>\n<h4>MAIN OUTCOME MEASURES:<\/h4>\n<p>The mean age was 27.4 years (6-44). The median length of symptoms was seven months (0.5-132). In the 2.8 years (1-6) of mean follow-up period, the disease recurred in 13 (11.6%) patients.<\/p>\n<h4>RESULTS:<\/h4>\n<p>This treatment procedure was well-tolerated by all the patients except for those who had unwanted results. No patients in group A had skin necrosis, and only one had abscesses. In group B two patients had abscesses, and three had skin necrosis. Fatty tissue necrosis was seen in one patient in Group A and in five patients in Group B. Recurrence rates were four (7.4%) cases in Group A and nine (15.5%) cases in Group B.<\/p>\n<h4>CONCLUSIONS:<\/h4>\n<p>It is possible to treat patients in a shorter time with a considerably smaller loss of working time, since the destruction of peripilonidal adipose tissue and skin is less. Therefore, the use of low-concentration phenol solution is an option to be considered in the treatment of PSD.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>OBJECTIVES: Many conservative methods have been applied in the treatment of pilonidal sinus disease (PSD). The most commonly used conservative treatment is 80% phenol solution. Our observations demonstrated that 80% phenol solution caused much destruction in the sacrococcygeal region. DESIGN: In this study low concentrations of phenol were used with the aim of reducing the [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":false,"_classifai_error":"","msr-author-ordering":null,"msr_publishername":"","msr_publisher_other":"","msr_booktitle":"","msr_chapter":"1","msr_edition":"","msr_editors":"","msr_how_published":"","msr_isbn":"","msr_issue":"","msr_journal":"JRSM Short 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