illustration of DNA strand and abstract shapes on a computer screen on a green gradient background

Medical, health, and genomics

Digital pathology helps decode tumor microenvironments for precision immunotherapy. GigaPath is a novel vision transformer that can scale to gigapixel whole-slide images by adapting dilated attention for digital pathology. In joint work with Providence and UW, we’re sharing Prov-GigaPath, the first whole-slide pathology foundation model pretrained on large-scale real-world data, for advancing clinical research and discovery.

GigaPath: Whole-Slide Foundation Model for Digital Pathology

Research Forum Ep2 | Panel | Transforming the Natural Sciences with AI

Research Forum 2 | Panel Discussion: Transforming the Natural Sciences with AI

white icons of first aid kit, DNA strand, laptop monitor with overlapping eye, and microscope on a blue and green gradient background

Scaling early detection of esophageal cancer with AI

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Microsoft Health Futures

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Microsoft Research Blog

MoLeR: Creating a path to more efficient drug design

April 27, 2022 | Krzysztof Maziarz, Marc Brockschmidt, Marwin Segler

Drug discovery has come a long way from its roots in serendipity. It is now an increasingly rational process, in which one important phase, called lead optimization, is the stepwise search for promising drug candidate…

Publication

T-cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibody titers and disease severity

Rebecca Elyanow, Thomas M. Snyder, Sudeb C. Dalai, Rachel M. Gittelman, Boonyaratanakornkit J, Wald A, Selke S, Wener Mh, Morishima C, Greninger Al, Michael Gale, Tien-Ying Hsiang, Lichen Jing, Holbrook Mr, Ian M. Kaplan, Damon H May, H. Jabran Zahid, Jonathan M. Carlson, Lance Baldo, Thomas Manley, Harlan S Robins, David M Koelle

JCI Insight | April 2022, Vol 7(10)

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Publication

Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection

Rachel M Gittelman, Enrico Lavezzo, Thomas M Snyder, H. Jabran Zahid, Cara L Carty, Rebecca Elyanow, Sudeb Dalai, Ilan Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola I Lorè, Dejan Lazarević, Daniela M Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan S Robins, Andrea Crisanti, Giovanni Tonon

JCI Insight | April 2022, Vol 7(10)

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Publication

FedKD: Communication Efficient Federated Learning via Knowledge Distillation.Communication-efficient federated learning via knowledge distillation

Chuhan Wu, Fangzhao Wu, Lingjuan Lyu, Yongfeng Huang, Xing Xie

Nature Communications | April 2022

Publication

Protease activity sensors enable real-time treatment response monitoring in lymphangioleiomyomatosis

Jesse D. Kirkpatrick, Ava P. Soleimany, Jaideep S. Dudani, Heng-Jia Liu, Hilaire C. Lam, Carmen Priolo, Elizabeth P. Henske, Sangeeta N. Bhatia

The European Respiratory Journal | April 2022, Vol 59

Publication

Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction

Jun Lan, Xinheng He, Yifei Ren, Ziyi Wang, Huan Zhou, Shilong Fan, Chenyou Zhu, Dongsheng Liu, Bin Shao, Tie-Yan Liu, Qisheng Wang, Linqi Zhang, Jiwan Ge, Tong Wang, Xinquan Wang

Cell Research | April 2022

Publication

Intimate Partner Violence as Reflected in Internet Search Data

Brit Youngmann, Elad Yom-Tov

Social Science Computer Review | April 2022

Project

Video

Introducing the Microsoft Africa Research Institute (MARI)

April 4, 2022 | Jacki O’Neill, Kagonya Awori, Samuel Maina, Maxamed Axmed, Najeeb Abdulhamid, Millicent Ochieng, Mercy Muchai, Stephanie Nyairo

The Microsoft Africa Research Institute is a new research institute located in Nairobi, Kenya. Our mission is to understand, build and deploy innovative cloud and AI technologies which not only address core opportunities in Africa…

03:27

Publication

Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States

EY Cramer, EL Ray, VK Lopez, J Bracher, A Brennen, [….], Juan M. Lavista Ferres

PNAS | April 2022

Project Project

Publication

Hierarchical Optimal Transport for Comparing Histopathology Datasets

Anna Yeaton, Rahul G Krishnan, Becky Mieloszyk, David Alvarez-Melis, Grace Huynh

April 2022

Medical, health, and genomics

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