illustration of DNA strand and abstract shapes on a computer screen on a green gradient background

Medical, health, and genomics

Digital pathology helps decode tumor microenvironments for precision immunotherapy. GigaPath is a novel vision transformer that can scale to gigapixel whole-slide images by adapting dilated attention for digital pathology. In joint work with Providence and UW, we’re sharing Prov-GigaPath, the first whole-slide pathology foundation model pretrained on large-scale real-world data, for advancing clinical research and discovery.

GigaPath: Whole-Slide Foundation Model for Digital Pathology

Research Forum Ep2 | Panel | Transforming the Natural Sciences with AI

Research Forum 2 | Panel Discussion: Transforming the Natural Sciences with AI

white icons of first aid kit, DNA strand, laptop monitor with overlapping eye, and microscope on a blue and green gradient background

Scaling early detection of esophageal cancer with AI

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Microsoft Health Futures

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Publication

Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection

Zabrina L. Brumme, Chanson J. Brumme, Jonathan M. Carlson, Hendrik Streeck, Mina John, Quentin Eichbaum, Brian L. Block, Brett Baker, Carl Kadie, Martin Markowitz, Heiko Jessen, Anthony D. Kelleher, Eric Rosenberg, John Kaldor, Yuko Yuki, Mary Carrington, Todd M. Allen, Simon Mallal, Marcus Altfeld, David Heckerman, Bruce D. Walker

Journal of Virology | January 2008, Vol 82: pp. 9216-9227

Github Project

Publication

HLA Class I-Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: immune Escape and Viral Load

Christine M. Rousseau, Marcus G. Daniels, Jonathan M. Carlson, Carl Kadie, Hayley Crawford, Andrew Prendergast, Philippa Matthews, Rebecca Payne, Morgane Rolland, Dana N. Raugi, Brandon S. Maust, Gerald H. Learn, David C. Nickle, Hoosen Coovadia, Thumbi Ndung'u, Nicole Frahm, Christian Brander, Bruce D. Walker, Philip J. R. Goulder, Tanmoy Bhattacharya, David Heckerman, Bette T. Korber, James I. Mullins

Journal of Virology | January 2008, Vol 82: pp. 6434-6446

Video

A Life Decoded: My Genome, My Life

November 16, 2007 | J. Craig Venter

One of the great landmarks in the history of science occurred when J. Craig Venter published the first sequence and analysis of the human genome, and did it earlier and for less money than the…

48:41

Publication

Executable Cell Biology

Jasmin Fisher

Nature Biotechnology | November 2007, Vol 25: pp. 1239-1249

See also correspondence in Nature Biotechnology 26(7):737-8;738-9, 2008.

Publication

Increased Cytotoxic T-Lymphocyte Epitope Variant Cross-Recognition and Functional Avidity Are Associated with Hepatitis C Virus Clearance

Daniel Yerly, David Heckerman, Todd M. Allen, John V. Chisholm III, Kellie Faircloth, Caitlyn H. Linde, Nicole Frahm, Joerg Timm, Werner J. Pichler, Andreas Cerny, Christian Brander

Journal of Virology | October 2007, Vol 82(6): pp. 3147-3153

Publication

A Statistical Framework for Modeling HLA-Dependent T Cell Response Data

Jennifer Listgarten, Nicole Frahm, Carl Kadie, Christian Brander, David Heckerman

PLoS Computational Biology | October 2007, Vol 4(10): pp. e188

Publication

Synthesizing Reactive Systems from LSC Requirements using the Play-Engine

Hillel Kugler, Cory Plock, Amir Pnueli

Companion to the 22nd ACM SIGPLAN conference on object oriented programming systems and applications (OOPSLA’07) | October 2007

Publication

Adaptive threshold QRS detector with best channel selection based on a noise rating system

Dimitra Emmanouilidou

Computing in Cardiology Conference | September 2007

Publication

SenseCam: A Wearable Camera can Help Improve Autobiographical Memory in Patients with Alzheimer’s Disease

Georgina Browne, Emma Berry, Steve Hodges, Lyndsay Williams, Gavin Smyth, Narinder Kapur, Alex Butler, Ken Woodberry

September 2007

Presentation at the Institute of Physics and Engineering in Medicine: Annual Scientific Meeting 2007, Cardiff

Project

Publication

Extensive HLA class I allele promiscuity among viral CTL epitopes

Nicole Frahm, Karina Yusim, Todd J. Suscovich, Sharon Adams, John Sidney, Peter Hraber, Hannah S. Hewitt, Caitlyn H. Linde, Daniel G. Kavanagh, Tonia Woodberry, Leah M. Henry, Kellie Faircloth, Jennifer Listgarten, Carl Kadie, Nebojsa Jojic, Kaori Sango, Nancy V. Brown, Eunice Pae, M. Tauheed Zaman, Florian Bihl, Ashok Khatri, Mina John, Simon Mallal, Francesco M. Marincola, Bruce D. Walker, Alessandro Sette, David Heckerman, Bette T. Korber, Christian Brander

European Journal of Immunology | September 2007, Vol 37(9): pp. 2419-2433

Medical, health, and genomics

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